After finishing the assay of methylbenzene residue in Taxol (Paclitaxel), found the 10 uL syringe clogged.The injection concentration is 0.2 g/ml. Maybe the high injection concentration is the reason why the syringe clogged.
Option 1: Try to put the syringe into MeOH with ultrasonic bath. But failed, the MeOH had difficulty to penetrate and dissolve the blockade.
Option 2: Put the needle in DMF bath for 2 hours, then if doesn’t work well, put ithe boiling water ( Boiling IPA) for 30 min. It worked.
Option 3: (learned it from Hamilton Tech Service) Put the clogged needle into MeOH or EtOH with ultrasonic bath over night.
